The facility, which will be located at Honda's Marysville-area plant, will be the first public CNG station on company property in North America.
The automaker said the project is part of an effort to reduce its global carbon dioxide emissions and minimize the environmental impact of its operations.
The fully automated fueling station will be designed, constructed and operated by Trillium CNG. It will feature three dispensers for over-the-road carriers and a separate dispenser for passenger and light-duty vehicles.
In the announcement, a Trillium executive said Ohio is a key state in the company's development plans. Trillium expects to operate 52 public-access CNG stations throughout the country by mid-summer.
Honda's station, at the interchange of U.S. Route 33 and state Route 739, is intended to serve current CNG users as well as to encourage others to expand the fuel's use.